Development and production of biopharmaceuticals is complex. Even minor impurities, or changes in attributes such as glycosylation or charge heterogeneity, can have a profound impact on the safety and efficacy of the final product.
The Multiple Attribute Methodology (MAM), an orthogonal approach based on peptide map separation coupled with high-resolution mass spectrometry, is rapidly emerging as a powerful tool for characterization and monitoring of biopharmaceutical attributes.
This technical note describes the use of SCIEX BioPharmaViewTM 3.0 Software for MAM workflow management. BioPharmaView software can manage all aspects of an MAM workflow from a single project. It eliminates the unnecessary complexity that comes with using multiple software packages.
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